On October 31, 2018, The Danish environment ministry published a major study that identified nine new substances as endocrine disrupting chemicals (EDCs) based on “solid scientific evidence”.
The nine chemicals identified as EDCs are:
- Prochloraz (CAS 67747-09-5)
- triclocarban (CAS 101-20-2)
- octamethylcyclotetrasiloxane (D4, CAS 556-67-2)
- tris(methylphenyl) phosphate (CAS 1330-78-5)
- salicylic acid (CAS 69-72-7)
- fenitrothion (CAS 122-14-5)
- di-n-pentylphthalate (CAS 131-18-0)
- bisphenol AF (BPAF, CAS 1478-61-1)
- isobutyl paraben (CAS 4247-02-3)
Salicylic acid is included in the Union List of substances authorized for use in plastic food contact materials (FCMs) (Annex I of Regulation (EU) No 10/2011), and D4 is also added to the REACH Candidate List of substances of very high concern (SVHCs) due to its very persistent and very bioaccumulative (vPvB) as well as persistent, bioaccumulative and toxic (PBT) properties. BPAF may currently be used as a replacement chemical for bisphenol A.