On 19 April, 2018, the Official Journal of the European Union released directive 2018/594, adding the benzene-1, 2, 4-tricarboxylic acid 1, 2 anhydride (trimellitic anhydride) (TMA) as a substance of very high concern. Up to now, the SVHC list is updated to 181 items.
Benzene-1, 2, 4-tricarboxylic acid 1, 2 anhydride (trimellitic anhydride) (TMA), EC No 209-008-0, CAS No 552-30-7, fulfils the criterion set out in Article 57(f) of Regulation (EC) No 1907/2006 (REACH). According to the Annex XV dossier, there is scientific evidence of probable serious effects to human health due to the respiratory sensitizing properties of TMA. The data shows that TMA causes serious and permanent impairment of lung functions, if the exposure is prolonged and no intervention takes place. TMA is identified as a substance of very high concern according to Article 57(f) of REACH Regulation due to its respiratory sensitising properties. Also it shall be included in the candidate list referred to in Article 59(1) of REACH Regulation with the following indication under ‘Reason for inclusion’ : ‘Respiratory sensitising properties (Article 57(f)) – human health’.